Customization: | Available |
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Function: | Antioxidant |
Certification: | GMP, ISO, HACCP |
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DESCRIPTION |
FUNCTION |
Antioxidant
The most characteristic components of the European Bilberry fruit are polyphenols, belonging to the class of anthocyanosides and proanthocyanidins. Its strong antioxidant activity contributes significantly to the protection of blood vessels. Many studies have reported that Bilberry Fruit Extract anthocyanosides strongly scavenge free radicals such as superoxide anion and other reactive oxygen species (ROS).
Beneficial for Vascular Health
The efficacy of bilberry fruit extracts in vascular health has been validated by numerous clinical assessments, including more than 50 empirical studies, including at least 25 controlled or double-blind studies. The vasoprotective effects of bilberry fruit extracts are associated with the ability to reduce capillary permeability and increase capillary tolerance through a combination of mechanisms, including stimulation of mucopolysaccharide biosynthesis, inhibition of proteolytic enzymes involved in the degradation of extravascular matrix components, and interactions with collagen metabolism. Of these, stimulation of mucopolysaccharide synthesis is thought to be key to the vasoprotective effects, as mucopolysaccharides play an important role in the physiological mechanisms of perivascular tissues.
Effects on Small Artery Vasomotion
Small artery vasomotion is a rhythmic change in the diameter of small arteries in the microvascular network used to regulate the process of interstitial fluid formation. Bilberry fruit extract 36% anthocyanin has been shown to induce small arterial vasomotion and increase the frequency of movement. This suggests that Vaccinium macrocarpon extract can prevent or control the formation of interstitial fluid and improve the distribution of blood flow in the microvascular network in general.
APPLICATION |
In the Food Field:
Bilberry extract powder is a food colorant with good color quality and wide color gamut, which can show different colors in acidic and weakly alkaline environments and can be added to different styles of food. The Joint FAO/WHO Expert Committee on Food Additives (JECFA) of the United Nations, based on the available toxicological information, considered that anthocyanosides are of "very low toxicity", and included them in the category of food additives of natural coloring. Bilberry extract is also classified as a non-certifiable food additive by the U.S. FDA and is permitted for use in beverages, dairy products, and pastries.
In the Functional Food:
A large number of phenolic hydroxyl groups contained in the molecule of anthocyanin in bilberry fruit can strongly fight against uncontrolled oxidation and free radical attack in the body, slow down or inhibit the aging and lesions of the human organism, which can be used as a functional ingredient of functional food, and can also be directly made into dietary supplements. Foreign health product manufacturers often compound anthocyanin with lutein to claim that it has a more perfect eyesight efficacy. Bilberry fruit extract powder is often used as a functional food additive.
In Pharmaceutical:
There are many experiments showing that anthocyanosides have antioxidant, apoptosis-inducing, and growth-suppressing effects on mammalian cells and inhibit inflammatory responses. Although anthocyanosides are highly water-soluble substances, experiments have confirmed that the presence of prototype anthocyanosides can be detected in cells, indicating that anthocyanosides can be absorbed by cells through cell membranes, which provides great convenience for the absorption and metabolism of anthocyanosides, and also provides great convenience for anthocyanosides in the form of applications in the pharmaceutical industry. In Europe, the extracts of bilberry fruit with the content of anthocyanosides greater than 24% are used as medicine, in the extracts of European bilberry anthocyanosides have been included in the pharmacopeias of Italy, Germany, and other countries.